Leukemia (blood cancer) is a type of cancer that attacks the blood cells caused by white blood cells produced by bone marrow abnormalities. Bone marrow in the human body produces three types of blood cells, among others:

a. White Blood Cells: Function as the immune system to fight infection
b. Red Blood Cells: Function to bring oxygen into the body
c. Platelets: Small portion of blood cells that function to help the process of blood clotting).

Someone with this condition (leukemia) will show some symptoms such as susceptible to infectious diseases, anemia and bleeding. Leukemia is generally appear in a person since the days small, bone marrow has been producing white blood cells do not develop normally without clear cause. Normally, white blood cells to repeated reproduction when the body needs it or if there is a place for the blood cell itself. The human body will give signs when will regularly be in the white blood cells reproduce again.

In cases of leukemia (blood cancer), white blood cells do not respond to signs given. Finally the production of white blood cells that excessive uncontrolled (abnormal) will exit from the bone marrow and can be found in the peripheral blood. The number of abnormal white blood cells of this excessive amount can disrupt the normal function of other cells.

# Is disease Acute and Chronic Leukemia?

Acute leukemia is marked by a process of very rapid progression of the disease, deteriorating, and deadly. If this does not immediately treated, it can cause death within weeks, even up to a matter of days. While chronic leukemia have disease processes that are not so quickly that it has a longer life expectancy, up to more than one year.

# What are the classification of leukemia?

Leukemia is classified according to cell type. When inspection reveals that affects lymphocyte leukemia or lymphoid cells, it is called lymphocytic leukemia. While the leukemia that affects cells such as neutrophils mieloid, basofil, and eosinophil, called chronic myelogenous leukemia.

From this classification, the Leukemia is divided into four types, namely:

1. Acute lymphocytic leukemia: A type of leukemia most commonly occurs in children. The disease is also found in adults, especially have been aged 65 years or more.
2. Acute myelogenous leukemia: Leukemia is more common in adults than children. This type formerly called nonlimfositik acute leukemia.
3. Chronic lymphocytic leukemia: This is often suffered by adults older than 55 years. Sometimes also suffered by young adults, and almost did not happen in children.
4. Chronic myelogenous leukemia: frequent in adults. Can also occur in children, but very little.

# Does Disease Cause Leukemia?

Until now, the cause of leukemia can not be known for certain, but there are several factors affecting the frequency of occurrence of leukemia.

1. Radiation. This is supported by some reports from some studies that deal with cases of leukemia, that the employees of radiology more often suffer from leukemia, patients with radiotherapy more often suffering from leukemia. This is reinforced by the fact Leukemia commonly found in victims of life events of Hiroshima and Nagasaki atomic bombs, Japan.

2. Leukemogenik. Several chemicals have been identified are reported can affect the frequency of leukemia, eg environmental toxins such as benzene, industrial chemicals such as insecticides, medicines used for chemotherapy.

3. Hereditary. Down Syndrome sufferers have an acute leukemia incidence 20 times greater than normal people.

4. Viruses. Some types of viruses can cause leukemia, such as retroviruses, feline leukemia virus, and HTLV-1 in adults.

# Are Signs and Symptoms of Leukemia Disease?

Leukemia symptoms caused generally different in each patient, however, can generally be described as follows:

1. Anemia. Patients will soon appear tired, pale and breathing fast (red blood cells below normal causing less oxygen in the body, resulting in the patient breathes faster to compensate for the fulfillment of oxygen in the body).

2. Bleeding. When Platelets (blood clotting cells) can not be produced with reasonable because dominated by white blood cells, then the patient will experience bleeding in the skin tissue (number of larvae wide red little skin).

3. Esophageal infection. White blood cells act as protective immunity, especially against infectious diseases. In Leukemia Patients, white blood cells formed are not normal, so that white blood cells do not function properly. As a result the body of the patient vulnerable to viral infection or bacteria, even by itself will reveal the existence of a complaint of fever, white-out fluid from the nose and cough.

4. Bones and Joints Pain. This is caused as a result of solid bone marrow urgently because the abnormal white blood cell production.

5. Stomach pain. Abdominal pain is also one indication of the symptoms of leukemia, where the leukemia cells may collect in kidney, liver and bile that causes enlargement of these organs. This may cause abdominal pain loss of appetite patients with leukemia.

6. Swollen Glands Lympa. Patients likely to experience swelling of the lymph glands, whether it is under the arm, neck, chest and others. Spleen is in charge of filtering the blood gland, leukemia cells can be collected here and cause swelling.

7. Difficulty breathing (dyspnea). Patients may exhibit symptoms of difficulty breathing and chest pain, if this happens then have to immediately get medical help.

# What mode Disease Diagnosis Leukemia (Blood Cancer)?

Leukaemia disease can be ascertained with some checks, such as by biopsy, Blood tests (complete blood count (CBC)), CT or CAT scan, magnetic resonance imaging (MRI), X-ray, Ultrasound, Spinal tap / lumbar puncture.

# How How To Handling and Treatment of Leukemia?

Handling cases of leukemia disease usually starts from the symptoms that arise, such as anemia, bleeding and infection. Broadly speaking the handling and treatment of leukemia can be done by a single or a combination of several methods below:

1. Chemotherapy / intrathecal medications
2. Radiation Therapy. This method is rarely used
Third. Bone marrow transplant
4. Provision of drugs and hypodermic tablets
5. Transfusions of red blood cells or platelets.

Therapy systems that are often used in dealing with patients with leukemia is a combination of chemotherapy and administration of drugs that focuses on the dismissal of production of abnormal white blood cells in the bone marrow. Next is the treatment of some symptoms and signs have been displayed by the patient’s body to monitor the komprehensive